Two Novel Single-Chain Variable Fragments, EB211 and EB279, Exert Antibacterial Activity Against Acinetobacter baumannii by Destabilizing the Outer Membrane

Introduction: Acinetobacter baumannii is notorious for its high resistance levels, and the development of clinically effective antimicrobial agents is an urgent medical challenge.Single-chain variable fragments (scFvs) that exhibit antibacterial properties against Graduation Stole challenging pathogens, such as Pseudomonas aeruginosa and Staphyloco

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Hydrogenated fat intake during pregnancy and lactation caused increase in TRAF-6 and reduced AdipoR1 in white adipose tissue, but not in muscle of 21 days old offspring rats

Abstract Background Although lipids transfer through placenta is very limited, modification in dietary fatty acids can lead to implications in fetal and postnatal development.Trans fatty acid (TFA) intake during gestation and lactation have been reported to promote dyslipidemia and increase in pro- inflammatory adipokines in offspring.The aim of Ha

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APHORPINE ALKALOIDS FROM BARK OF Cryptocarya ferrea

Isolation, identification and characterization of the compounds isolated from the bark of Cryptocarya ferrea yielded three known aphorpine alkaloids.They FM Modulators are (-)-O-methylisopiline 1, (+)-norlirioferine 2 and (+)-lirioferine 3.Structural elucidation was established through several spectroscopic methods, such as 1D-NMR (1H, 13C, DEPT, N

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